Rationale and design of mDOT-HuA study: a randomized trial to assess the effect of mobile-directly observed therapy on adherence to hydroxyurea in adults with sickle cell anemia in Tanzania

BACKGROUND: Hydroxyurea (HU) has been demonstrated to be efficacious in reducing complications in individuals with sickle cell anemia (SCA) but poor adherence is a barrier. Directly Observed Therapy (DOT) has been shown to improve adherence in various chronic diseases but there is limited data in ad...

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書目詳細資料
發表在:BMC Med Res Methodol
Main Authors: Makubi, Abel, Sasi, Philip, Ngaeje, Mariam, Novelli, Enrico M., Mmbando, Bruno P., Gladwin, Mark T., Makani, Julie
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Study Protocol
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069827/
https://ncbi.nlm.nih.gov/pubmed/27756209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-016-0245-9
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