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Stabilization of the E3 Ubiquitin Ligase Nrdp1 by the Deubiquitinating Enzyme USP8

Nrdp1 is a RING finger-containing E3 ubiquitin ligase that physically interacts with and regulates steady-state cellular levels of the ErbB3 and ErbB4 receptor tyrosine kinases and has been implicated in the degradation of the inhibitor-of-apoptosis protein BRUCE. Here we demonstrate that the Nrdp1...

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Detalles Bibliográficos
Main Authors: Wu, Xiuli, Yen, Lily, Irwin, Lisa, Sweeney, Colleen, Carraway, Kermit L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC506982/
https://ncbi.nlm.nih.gov/pubmed/15314180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7748-7757.2004
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