Jun Blockade of Erythropoiesis: Role for Repression of GATA-1 by HERP2

Although Jun upregulation and activation have been established as critical to oncogenesis, the relevant downstream pathways remain incompletely characterized. In this study, we found that c-Jun blocks erythroid differentiation in primary human hematopoietic progenitors and, correspondingly, that Jun...

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Autors principals: Elagib, Kamaleldin E., Xiao, Mang, Hussaini, Isa M., Delehanty, Lorrie L., Palmer, Lisa A., Racke, Frederick K., Birrer, Michael J., Shanmugasundaram, Ganapath, McDevitt, Michael A., Goldfarb, Adam N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
Matèries:
Transcriptional Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC506977/
https://ncbi.nlm.nih.gov/pubmed/15314183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7779-7794.2004
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