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Inhibition of HDM2 and Activation of p53 by Ribosomal Protein L23

The importance of coordinating cell growth with proliferation has been recognized for a long time. The molecular basis of this relationship, however, is poorly understood. Here we show that the ribosomal protein L23 interacts with HDM2. The interaction involves the central acidic domain of HDM2 and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jin, Aiwen, Itahana, Koji, O'Keefe, Kevin, Zhang, Yanping
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC506972/
https://ncbi.nlm.nih.gov/pubmed/15314174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7669-7680.2004
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