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Inhibition of HDM2 and Activation of p53 by Ribosomal Protein L23

The importance of coordinating cell growth with proliferation has been recognized for a long time. The molecular basis of this relationship, however, is poorly understood. Here we show that the ribosomal protein L23 interacts with HDM2. The interaction involves the central acidic domain of HDM2 and...

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Autori principali: Jin, Aiwen, Itahana, Koji, O'Keefe, Kevin, Zhang, Yanping
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC506972/
https://ncbi.nlm.nih.gov/pubmed/15314174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7669-7680.2004
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