Ribosomal Protein L23 Activates p53 by Inhibiting MDM2 Function in Response to Ribosomal Perturbation but Not to Translation Inhibition

The p53-MDM2 feedback loop is vital for cell growth control and is subjected to multiple regulations in response to various stress signals. Here we report another regulator of this loop. Using an immunoaffinity method, we purified an MDM2-associated protein complex that contains the ribosomal protei...

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Bibliografiske detaljer
Main Authors: Dai, Mu-Shui, Zeng, Shelya X., Jin, Yetao, Sun, Xiao-Xin, David, Larry, Lu, Hua
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC506971/
https://ncbi.nlm.nih.gov/pubmed/15314173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7654-7668.2004
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