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Zinc(II) Binding Site to the Amyloid-β Peptide: Insights from Spectroscopic Studies with a Wide Series of Modified Peptides
[Image: see text] The Zn(II) ion has been linked to Alzheimer’s disease (AD) due to its ability to modulate the aggregating properties of the amyloid-β (Aβ) peptide, where Aβ aggregation is a central event in the etiology of the disease. Delineating Zn(II) binding properties to Aβ is thus a prerequi...
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| Publicado no: | Inorg Chem |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2016
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5069684/ https://ncbi.nlm.nih.gov/pubmed/27665863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.inorgchem.6b01733 |
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