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Replication and Cytopathic Effect of Oncolytic Vesicular Stomatitis Virus in Hypoxic Tumor Cells In Vitro and In Vivo

Tumor hypoxia presents an obstacle to the effectiveness of most antitumor therapies, including treatment with oncolytic viruses. In particular, an oncolytic virus must be resistant to the inhibition of DNA, RNA, and protein synthesis that occurs during hypoxic stress. Here we show that vesicular sto...

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מידע ביבליוגרפי
Main Authors: Connor, John H., Naczki, Christine, Koumenis, Costas, Lyles, Douglas S.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2004
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC506958/
https://ncbi.nlm.nih.gov/pubmed/15308693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.8960-8970.2004
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