Wird geladen...

Indoxyl Sulfate Enhance the Hypermethylation of Klotho and Promote the Process of Vascular Calcification in Chronic Kidney Disease

Chronic kidney disease (CKD) is a state of Klotho deficiency. The Klotho expression may be suppressed due to DNA hypermethylation in cancer cells so we have investigated the effects and possible mechanisms by which Klotho expression is regulated in human aortic smooth muscle cells (HASMCs). The vasc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Int J Biol Sci
Hauptverfasser: Chen, Jing, Zhang, Xiaoyan, Zhang, Han, Liu, Tongqiang, Zhang, Hui, Teng, Jie, Ji, Jun, Ding, Xiaoqiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ivyspring International Publisher 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069445/
https://ncbi.nlm.nih.gov/pubmed/27766038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.15195
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!