Model Suggesting that Replication of Influenza Virus Is Regulated by Stabilization of Replicative Intermediates

The RNA-dependent RNA polymerase of influenza A virus is responsible for both transcription and replication of negative-sense viral RNA. It is thought that a “switching” mechanism regulates the transition between these activities. We demonstrate that, in the presence of preexisting viral RNA polymer...

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Hlavní autoři: Vreede, Frank T., Jung, Tanis E., Brownlee, George G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Replication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC506943/
https://ncbi.nlm.nih.gov/pubmed/15308750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.9568-9572.2004
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