Characterization of a Thermostable 8-Oxoguanine DNA Glycosylase Specific for GO/N Mismatches from the Thermoacidophilic Archaeon Thermoplasma volcanium

The oxidation of guanine (G) to 7,8-dihydro-8-oxoguanine (GO) forms one of the major DNA lesions generated by reactive oxygen species (ROS). The GO can be corrected by GO DNA glycosylases (Ogg), enzymes involved in base excision repair (BER). Unrepaired GO induces mismatched base pairing with adenin...

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Detalhes bibliográficos
Publicado no:Archaea
Main Authors: Fujii, Miki, Hata, Chieri, Ukita, Munetada, Fukushima, Chie, Matsuura, Chihiro, Kawashima-Ohya, Yoshie, Tomobe, Koji, Kawashima, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069365/
https://ncbi.nlm.nih.gov/pubmed/27799846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8734894
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