Characterization of a Thermostable 8-Oxoguanine DNA Glycosylase Specific for GO/N Mismatches from the Thermoacidophilic Archaeon Thermoplasma volcanium

The oxidation of guanine (G) to 7,8-dihydro-8-oxoguanine (GO) forms one of the major DNA lesions generated by reactive oxygen species (ROS). The GO can be corrected by GO DNA glycosylases (Ogg), enzymes involved in base excision repair (BER). Unrepaired GO induces mismatched base pairing with adenin...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Archaea
Päätekijät: Fujii, Miki, Hata, Chieri, Ukita, Munetada, Fukushima, Chie, Matsuura, Chihiro, Kawashima-Ohya, Yoshie, Tomobe, Koji, Kawashima, Tsuyoshi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2016
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069365/
https://ncbi.nlm.nih.gov/pubmed/27799846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8734894
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