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Characterization of the DNA Gyrase from the Thermoacidophilic Archaeon Thermoplasma acidophilum
Thermoplasma acidophilum is sensitive to the antibiotic drug novobiocin, which inhibits DNA gyrase. We characterized DNA gyrases from T. acidophilum strains in vitro. The DNA gyrase from a novobiocin-resistant strain and an engineered mutant were less sensitive to novobiocin. The novobiocin-resistan...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1316996/ https://ncbi.nlm.nih.gov/pubmed/16321962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.24.8531-8536.2005 |
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