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Subcellular Localization and Calcium and pH Requirements for Proteolytic Processing of the Hendra Virus Fusion Protein

Proteolytic cleavage of the Hendra virus fusion (F) protein results in the formation of disulfide-linked F(1) and F(2) subunits, with cleavage occurring after residue K(109) in the sequence GDVK↓L. This unusual cleavage site and efficient propagation of Hendra virus in a furin-deficient cell line in...

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Main Authors: Pager, Cara Theresia, Wurth, Mark Allen, Dutch, Rebecca Ellis
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC506929/
https://ncbi.nlm.nih.gov/pubmed/15308711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.9154-9163.2004
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