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Roscovitine Inhibits Activation of Promoters in Herpes Simplex Virus Type 1 Genomes Independently of Promoter-Specific Factors

Flavopiridol, roscovitine, and other inhibitors of Cyclin-Dependent Kinases (CDK) inhibit the replication of a variety of viruses in vitro while proving nontoxic in human clinical trials of their effects against cancer. Consequently, these and other Pharmacological CDK inhibitors (PCIs) have been pr...

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Autors principals: Diwan, Prerna, Lacasse, Jonathan J., Schang, Luis M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC506918/
https://ncbi.nlm.nih.gov/pubmed/15308730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.17.9352-9365.2004
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