The Cyclin-Dependent Kinase Inhibitor Roscovitine Inhibits the Transactivating Activity and Alters the Posttranslational Modification of Herpes Simplex Virus Type 1 ICP0

The cyclin-dependent kinase (cdk) inhibitor Roscovitine (Rosco) reduces transcription of herpes simplex virus early genes significantly, even in the presence of wild-type levels of immediate-early (IE) viral proteins, suggesting that the transactivating functions of IE proteins may require the activ...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Davido, David J., Leib, David A., Schaffer, Priscilla A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11773384/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.3.1077-1088.2002
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