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Targeting ADAM17 in leukocytes increases neutrophil recruitment and reduces bacterial spread during polymicrobial sepsis

A rapid and robust recruitment of circulating neutrophils at sites of infection is critical for preventing bacterial spread. The efficiency of this process, however, is greatly diminished during sepsis, a severe systemic inflammatory response to infection. The proteolytic activity of a disintegrin a...

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Bibliografski detalji
Izdano u:J Leukoc Biol
Glavni autori: Mishra, Hemant K, Johnson, Timothy J., Seelig, Davis M., Walcheck, Bruce
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069091/
https://ncbi.nlm.nih.gov/pubmed/27059842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3VMAB1115-496RR
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