Absence of CCR2 results in an inflammaging environment in young mice with age-independent impairments in muscle regeneration

Skeletal muscle regeneration requires coordination between dynamic cellular populations and tissue microenvironments. Macrophages, recruited via CCR2, are essential for regeneration; however, the contribution of macrophages and the role of CCR2 on nonhematopoietic cells has not been defined. In addi...

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Bibliografiske detaljer
Udgivet i:J Leukoc Biol
Main Authors: Melton, David W., Roberts, Alexander C., Wang, Hanzhou, Sarwar, Zaheer, Wetzel, Michael D., Wells, Jason T., Porter, Laurel, Berton, Michael T., McManus, Linda M., Shireman, Paula K.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Leukocyte Biology 2016
Fag:
Primary Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5069084/
https://ncbi.nlm.nih.gov/pubmed/27531927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3MA0316-104R
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