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Regulation of skeletal muscle regeneration by CCR2-activating chemokines is directly related to macrophage recruitment

Muscle regeneration requires CC chemokine receptor 2 (CCR2) expression on bone marrow-derived cells; macrophages are a prominent CCR2-expressing cell in this process. CCR2−/− mice have severe impairments in angiogenesis, macrophage recruitment, and skeletal muscle regeneration following cardiotoxin...

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Detalhes bibliográficos
Main Authors: Martinez, Carlo O., McHale, Matthew J., Wells, Jason T., Ochoa, Oscar, Michalek, Joel E., McManus, Linda M., Shireman, Paula K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944434/
https://ncbi.nlm.nih.gov/pubmed/20631294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00797.2009
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