Preservation Analysis of Macrophage Gene Coexpression Between Human and Mouse Identifies PARK2 as a Genetically Controlled Master Regulator of Oxidative Phosphorylation in Humans

Macrophages are key players involved in numerous pathophysiological pathways and an in-depth characterization of their gene regulatory networks can help in better understanding how their dysfunction may impact on human diseases. We here conducted a cross-species network analysis of macrophage gene e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:G3 (Bethesda)
Prif Awduron: Codoni, Veronica, Blum, Yuna, Civelek, Mete, Proust, Carole, Franzén, Oscar, Björkegren, Johan L. M., Le Goff, Wilfried, Cambien, Francois, Lusis, Aldons J., Trégouët, David-Alexandre
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2016
Pynciau:
Investigations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068955/
https://ncbi.nlm.nih.gov/pubmed/27558669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.033894
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