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Mms21 SUMO Ligase Activity Promotes Nucleolar Function in Saccharomyces cerevisiae
The budding yeast E3 SUMO ligase Mms21, also known as Nse2, is a component of the Smc5/6 complex, which regulates sister chromatid cohesion, DNA replication, and repair. Our study shows that the mms21RINGΔ mutant exhibits (1) reduced ribosomal RNA production; (2) nuclear accumulation of ribosomal pr...
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| Publicado no: | Genetics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068852/ https://ncbi.nlm.nih.gov/pubmed/27510371 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.181750 |
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