Llwytho...

Mms21 SUMO Ligase Activity Promotes Nucleolar Function in Saccharomyces cerevisiae

The budding yeast E3 SUMO ligase Mms21, also known as Nse2, is a component of the Smc5/6 complex, which regulates sister chromatid cohesion, DNA replication, and repair. Our study shows that the mms21RINGΔ mutant exhibits (1) reduced ribosomal RNA production; (2) nuclear accumulation of ribosomal pr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genetics
Prif Awduron: Kim, Dong-Hwan, Harris, Bethany, Wang, Fei, Seidel, Chris, McCroskey, Scott, Gerton, Jennifer L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Genetics Society of America 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068852/
https://ncbi.nlm.nih.gov/pubmed/27510371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.181750
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!