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Comparing the Statistical Fate of Paralogous and Orthologous Sequences

For several decades, sequence alignment has been a widely used tool in bioinformatics. For instance, finding homologous sequences with a known function in large databases is used to get insight into the function of nonannotated genomic regions. Very efficient tools like BLAST have been developed to...

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Publicado en:Genetics
Main Authors: Massip, Florian, Sheinman, Michael, Schbath, Sophie, Arndt, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068840/
https://ncbi.nlm.nih.gov/pubmed/27474728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.193912
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