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Next-Generation Sequencing-Based Approaches for Mutation Mapping and Identification in Caenorhabditis elegans

The use of next-generation sequencing (NGS) has revolutionized the way phenotypic traits are assigned to genes. In this review, we describe NGS-based methods for mapping a mutation and identifying its molecular identity, with an emphasis on applications in Caenorhabditis elegans. In addition to an o...

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Foilsithe in:Genetics
Main Authors: Doitsidou, Maria, Jarriault, Sophie, Poole, Richard J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068839/
https://ncbi.nlm.nih.gov/pubmed/27729495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.115.186197
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