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Progesterone induces progesterone receptor gene (PGR) expression via rapid activation of protein kinase pathways required for cooperative estrogen receptor alpha (ER) and progesterone receptor (PR) genomic action at ER/PR target genes
Progesterone Receptors (PRs) are critical effectors of estrogen receptor (ER) signaling required for mammary gland development and reproductive proficiency. In breast and reproductive tract malignancies, PR expression is a clinical prognostic marker of ER action. While estrogens primarily regulate P...
Bewaard in:
Gepubliceerd in: | Steroids |
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Hoofdauteurs: | , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068826/ https://ncbi.nlm.nih.gov/pubmed/27641443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2016.09.004 |
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