Progesterone induces progesterone receptor gene (PGR) expression via rapid activation of protein kinase pathways required for cooperative estrogen receptor alpha (ER) and progesterone receptor (PR) genomic action at ER/PR target genes

Progesterone Receptors (PRs) are critical effectors of estrogen receptor (ER) signaling required for mammary gland development and reproductive proficiency. In breast and reproductive tract malignancies, PR expression is a clinical prognostic marker of ER action. While estrogens primarily regulate P...

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Publicat a:Steroids
Autors principals: Diep, Caroline H., Ahrendt, Hannah, Lange, Carol A.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068826/
https://ncbi.nlm.nih.gov/pubmed/27641443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.steroids.2016.09.004
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