Deciphering H3K4me3 broad domains associated with gene-regulatory networks and conserved epigenomic landscapes in the human brain

Regulators of the histone H3-trimethyl lysine-4 (H3K4me3) mark are significantly associated with the genetic risk architecture of common neurodevelopmental disease, including schizophrenia and autism. Typical H3K4me3 is primarily localized in the form of sharp peaks, extending in neuronal chromatin...

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Publicado en:Transl Psychiatry
Autores principales: Dincer, A, Gavin, D P, Xu, K, Zhang, B, Dudley, J T, Schadt, E E, Akbarian, S
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2015
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068762/
https://ncbi.nlm.nih.gov/pubmed/26575220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2015.169
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