A procedure for the analysis of site-specific and structure-specific fucosylation in alpha-1-antitrypsin

A MS-based methodology has been developed for analysis of core-fucosylated versus antennary-fucosylated glycosites in glycoproteins. This procedure is applied to the glycoprotein alpha-1-antitrypsin (A1AT), which contains both core- and antennary-fucosylated glycosites. The workflow involves digesti...

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Udgivet i:Electrophoresis
Main Authors: Yin, Haidi, Zhu, Jianhui, Wu, Jing, Tan, Zhijing, An, Mingrui, Zhou, Shiyue, Mechref, Yehia, Lubman, David M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068566/
https://ncbi.nlm.nih.gov/pubmed/27439567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/elps.201600176
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