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Defining the clonal dynamics leading to mouse skin tumour initiation

The changes that occur in cell dynamics following oncogenic mutation that lead to the development of tumours are currently unknown. Here, using skin epidermis as a model, we assessed the impact of oncogenic hedgehog signalling in distinct cell populations and their capacity to induce basal cell carc...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Sánchez-Danés, Adriana, Hannezo, Edouard, Larsimont, Jean-Christophe, Liagre, Mélanie, Youssef, Khalil Kass, Simons, Benjamin D, Blanpain, Cédric
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068560/
https://ncbi.nlm.nih.gov/pubmed/27459053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19069
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