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Defining the clonal dynamics leading to mouse skin tumour initiation

The changes that occur in cell dynamics following oncogenic mutation that lead to the development of tumours are currently unknown. Here, using skin epidermis as a model, we assessed the impact of oncogenic hedgehog signalling in distinct cell populations and their capacity to induce basal cell carc...

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Foilsithe in:Nature
Main Authors: Sánchez-Danés, Adriana, Hannezo, Edouard, Larsimont, Jean-Christophe, Liagre, Mélanie, Youssef, Khalil Kass, Simons, Benjamin D, Blanpain, Cédric
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068560/
https://ncbi.nlm.nih.gov/pubmed/27459053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19069
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