NS1 Protein Mutation I64T Affects Interferon Responses and Virulence of Circulating H3N2 Human Influenza A Viruses

Influenza NS1 protein is the main viral protein counteracting host innate immune responses, allowing the virus to efficiently replicate in interferon (IFN)-competent systems. In this study, we analyzed NS1 protein variability within influenza A (IAV) H3N2 viruses infecting humans during the 2012-201...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: DeDiego, Marta L., Nogales, Aitor, Lambert-Emo, Kris, Martinez-Sobrido, Luis, Topham, David J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2016
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068522/
https://ncbi.nlm.nih.gov/pubmed/27535054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01039-16
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