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Codon usage is an important determinant of gene expression levels largely through its effects on transcription
Codon usage biases are found in all eukaryotic and prokaryotic genomes, and preferred codons are more frequently used in highly expressed genes. The effects of codon usage on gene expression were previously thought to be mainly mediated by its impacts on translation. Here, we show that codon usage s...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5068308/ https://ncbi.nlm.nih.gov/pubmed/27671647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606724113 |
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