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Follicular dendritic cell disruption as a novel mechanism of virus-induced immunosuppression

Arboviruses cause acute diseases that increasingly affect global health. We used bluetongue virus (BTV) and its natural sheep host to reveal a previously uncharacterized mechanism used by an arbovirus to manipulate host immunity. Our study shows that BTV, similarly to other antigens delivered throug...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Melzi, Eleonora, Caporale, Marco, Rocchi, Mara, Martín, Verónica, Gamino, Virginia, di Provvido, Andrea, Marruchella, Giuseppe, Entrican, Gary, Sevilla, Noemí, Palmarini, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068271/
https://ncbi.nlm.nih.gov/pubmed/27671646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610012113
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