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Label-Free Detection of Glycan–Protein Interactions for Array Development by Surface-Enhanced Raman Spectroscopy (SERS)

A glyco-array platform has been developed, in which glycans are attached to plasmonic nanoparticles through strain-promoted azide-alkyne cycloaddition. Glycan–protein binding events can then be detected in a label-free manner employing surface-enhanced Raman spectroscopy (SERS). As proof of concept,...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Li, Xiuru, Martin, Sharon J. H., Chinoy, Zoeisha S., Liu, Lin, Rittgers, Brandon, Dluhy, Richard A., Boons, Geert-Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067739/
https://ncbi.nlm.nih.gov/pubmed/27304194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201602706
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