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Activated Factor X Induces Endothelial Cell Senescence Through IGFBP-5

Uncontrolled coagulation contributes to the pathophysiology of several chronic inflammatory diseases. In these conditions, senescent cells are often observed and is involved in the generation of inflammation. The coincidence of hyper-coagulation, cell senescence, and inflammation suggests the existe...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sanada, Fumihiro, Taniyama, Yoshiaki, Muratsu, Jun, Otsu, Rei, Iwabayashi, Masaaki, Carracedo, Miguel, Rakugi, Hiromi, Morishita, Ryuichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067718/
https://ncbi.nlm.nih.gov/pubmed/27752126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35580
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