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Formation of guide RNA/messenger RNA chimeric molecules in vitro, the initial step of RNA editing, is dependent on an anchor sequence.

Synthetic pre-edited messenger RNA (mRNA) and guide RNA (gRNA) for the 5'-edited maxicircle-encoded ND7 cryptogene from Leishmania tarentolae formed chimeric molecules upon incubation in the presence of a mitochondrial extract. These chimeric molecules consisted of the gRNAs covalently linked to the...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Blum, B, Simpson, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1992
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1465424/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.24.11944
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