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Improving the Efficiency of CRISPR Ribonucleoprotein-Mediated Precise Gene Editing by Small Molecules in Porcine Fibroblasts

The aim of this study was to verify whether small molecules can improve the efficiency of precision gene editing using clustered regularly interspaced short palindromic repeats (CRISPR) ribonucleoprotein (RNP) in porcine cells. CRISPR associated 9 (Cas9) protein, small guide RNA (sgRNA), phosphoroth...

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Principais autores: Yunjing Zhao, Xinyu Li, Chang Liu, Chaoqian Jiang, Xiaochen Guo, Qianqian Xu, Zhi Yin, Zhonghua Liu, Yanshuang Mu
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2024-02-01
סדרה:Animals
נושאים:
pig
CRISPR/Cas9
small molecule
precise gene editing
HDR
גישה מקוונת:https://www.mdpi.com/2076-2615/14/5/719
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