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TET2 mutations were predictive of inferior prognosis in the presence of ASXL1 mutations in patients with chronic myelomonocytic leukemia

BACKGROUND: Somatic mutations involving epigenetic regulators, histone modification and chromatin regulation, splicing components, transcription factors and signaling regulator genes are common in chronic myelomonocytic leukemia (CMML) patients. It has been consensus that ASXL1 mutations have advers...

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I publikationen:Stem Cell Investig
Huvudupphovsmän: Cui, Yajuan, Tong, Hongyan, Du, Xin, Li, Bing, Gale, Robert Peter, Qin, Tiejun, Liu, Jinqin, Xu, Zefeng, Zhang, Yue, Huang, Gang, Jin, Jie, Fang, Liwei, Zhang, Hongli, Pan, Lijuan, Hu, Naibo, Qu, Shiqiang, Xiao, Zhijian
Materialtyp: Artigo
Språk:Inglês
Publicerad: AME Publishing Company 2016
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067368/
https://ncbi.nlm.nih.gov/pubmed/27777939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/sci.2016.09.04
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