Impact of TET2, SRSF2, ASXL1 and SETBP1 mutations on survival of patients with chronic myelomonocytic leukemia

BACKGROUND: Chronic myelomonocytic leukemia (CMML) is a myeloid neoplasm classified in the myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) category. Molecular abnormalities are reported in about 90 % of patients with CMML. ASXL1 and SETBP1 mutations, but not TET2 or SFRS2 mutations ar...

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Enregistré dans:
Détails bibliographiques
Publié dans:Exp Hematol Oncol
Auteurs principaux: Cui, Yajuan, Tong, Hongyan, Du, Xin, Li, Bing, Gale, Robert Peter, Qin, Tiejun, Liu, Jinqin, Xu, Zefeng, Zhang, Yue, Huang, Gang, Jin, Jie, Fang, Liwei, Zhang, Hongli, Pan, Lijuan, Hu, Naibo, Qu, Shiqiang, Xiao, Zhijian
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445804/
https://ncbi.nlm.nih.gov/pubmed/26019984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-015-0009-y
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