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Loss of Dendritic Complexity Precedes Neurodegeneration in a Mouse Model with Disrupted Mitochondrial Distribution in Mature Dendrites

Correct mitochondrial distribution is critical for satisfying local energy demands and calcium buffering requirements and supporting key cellular processes. The mitochondrially targeted proteins Miro1 and Miro2 are important components of the mitochondrial transport machinery, but their specific rol...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: López-Doménech, Guillermo, Higgs, Nathalie F., Vaccaro, Victoria, Roš, Hana, Arancibia-Cárcamo, I. Lorena, MacAskill, Andrew F., Kittler, Josef T.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067282/
https://ncbi.nlm.nih.gov/pubmed/27705781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.09.004
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