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TUT7 catalyzes the uridylation of the 3′ end for rapid degradation of histone mRNA
The replication-dependent histone mRNAs end in a stem–loop instead of the poly(A) tail present at the 3′ end of all other cellular mRNAs. Following processing, the 3′ end of histone mRNAs is trimmed to 3 nucleotides (nt) after the stem–loop, and this length is maintained by addition of nontemplated...
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| Publicado no: | RNA |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5066620/ https://ncbi.nlm.nih.gov/pubmed/27609902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.058107.116 |
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