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Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation

Current rescue therapies for life-threatening arrhythmias ignore the pathological electro-anatomical substrate and base their efficacy on a generalized electrical discharge. Here, we developed an all-optical platform to examine less invasive defibrillation strategies. An ultrafast wide-field macrosc...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Crocini, Claudia, Ferrantini, Cecilia, Coppini, Raffaele, Scardigli, Marina, Yan, Ping, Loew, Leslie M., Smith, Godfrey, Cerbai, Elisabetta, Poggesi, Corrado, Pavone, Francesco S., Sacconi, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066272/
https://ncbi.nlm.nih.gov/pubmed/27748433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35628
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