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Discovery of Fluorescence Polarization Probe for the ELISA-Based Antagonist Screening of α(1)-Adrenergic Receptors

[Image: see text] High-throughput screening (HTS) of ligand library to find new active molecules for G protein-coupled receptors is still a major interest, as well as an actual challenge. Fluorescence polarization (FP) assay portrays an essential role in HTS; however, in many cases, it was restricte...

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Pubblicato in:ACS Med Chem Lett
Autori principali: Ma, Zhao, Liu, Zhenzhen, Jiang, Tianyu, Zhang, Tianchao, Zhang, Huateng, Du, Lupei, Li, Minyong
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2016
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5066147/
https://ncbi.nlm.nih.gov/pubmed/27774138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00048
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