Hematopoietic stem cell transplantation: Improving alloreactive Bw4 donor selection by genotyping codon 86 of KIR3DL1/S1

KIR3DL1 is a Natural Killer (NK) cell receptor that recognizes the Bw4 epitope of HLA class I molecules. Following hematopoietic stem cell transplantation for patients lacking Bw4, KIR3DL1-expressing NK cells from Bw4-positive donors can be alloreactive and eliminate tumour cells. However, KIR3DL1 a...

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Udgivet i:Eur J Immunol
Main Authors: Alicata, Claudia, Pende, Daniela, Meazza, Raffaella, Canevali, Paolo, Loiacono, Fabrizio, Bertaina, Alice, Locatelli, Franco, Nemat-Gorgani, Neda, Guethlein, Lisbeth. A., Parham, Peter, Moretta, Lorenzo, Moretta, Alessandro, Bottino, Cristina, Norman, Paul J., Falco, Michela
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065926/
https://ncbi.nlm.nih.gov/pubmed/26990677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201546236
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