Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice

Oxidative stress plays an important role in cerebral ischemia–reperfusion injury. Dimethyl fumarate (DMF) and its primary metabolite monomethyl fumarate (MMF) are antioxidant agents that can activate the nuclear factor erythroid-2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway and induce th...

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Detalhes bibliográficos
Publicado no:Transl Stroke Res
Main Authors: Yao, Yang, Miao, Weimin, Liu, Zhijia, Han, Wei, Shi, Kaibin, Shen, Yi, Li, Handong, Liu, Qiang, Fu, Ying, Huang, DeRen, Shi, Fu-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065588/
https://ncbi.nlm.nih.gov/pubmed/27614618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-016-0496-0
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