Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice

Oxidative stress plays an important role in cerebral ischemia–reperfusion injury. Dimethyl fumarate (DMF) and its primary metabolite monomethyl fumarate (MMF) are antioxidant agents that can activate the nuclear factor erythroid-2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) pathway and induce th...

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Pubblicato in:Transl Stroke Res
Autori principali: Yao, Yang, Miao, Weimin, Liu, Zhijia, Han, Wei, Shi, Kaibin, Shen, Yi, Li, Handong, Liu, Qiang, Fu, Ying, Huang, DeRen, Shi, Fu-Dong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065588/
https://ncbi.nlm.nih.gov/pubmed/27614618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-016-0496-0
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