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Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation

RATIONALE: We have previously shown that innate immunity is necessary for transdifferentiation of fibroblasts to endothelial cells. A major signaling molecule involved in innate immunity is inducible nitric oxide synthase (iNOS). Accordingly, we hypothesized that iNOS-generated nitric oxide (NO) mig...

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Dettagli Bibliografici
Pubblicato in:Circ Res
Autori principali: Meng, Shu, Zhou, Gang, Gu, Qilin, Chanda, Palas K., Ospino, Frank, Cooke, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065398/
https://ncbi.nlm.nih.gov/pubmed/27623813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308263
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