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Hypoxia Imaging With PET Correlates With Antitumor Activity of the Hypoxia-Activated Prodrug Evofosfamide (TH-302) in Rodent Glioma Models

High-grade gliomas are often characterized by hypoxia, which is associated with both poor long-term prognosis and therapy resistance. The adverse role hypoxia plays in treatment resistance and disease progression has led to the development of hypoxia imaging methods and hypoxia-targeted treatments....

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Bibliografske podrobnosti
izdano v:Tomography
Main Authors: Stokes, Ashley M., Hart, Charles P., Quarles, C. Chad
Format: Artigo
Jezik:Inglês
Izdano: Grapho Publications, LLC 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065246/
https://ncbi.nlm.nih.gov/pubmed/27752544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18383/j.tom.2016.00259
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