A Clostridium difficile Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence

Clostridium difficile is a diarrheagenic pathogen associated with significant mortality and morbidity. While its glucosylating toxins are primary virulence determinants, there is increasing appreciation of important roles for non-toxin factors in C. difficile pathogenesis. Cell wall glycopolymers (C...

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Publicado en:PLoS Pathog
Autores principales: Chu, Michele, Mallozzi, Michael J. G., Roxas, Bryan P., Bertolo, Lisa, Monteiro, Mario A., Agellon, Al, Viswanathan, V. K., Vedantam, Gayatri
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065235/
https://ncbi.nlm.nih.gov/pubmed/27741317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005946
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