Striatal GDNF Production Is Independent to Circulating Estradiol Level Despite Pan-Neuronal Activation in the Female Mouse

Gender difference in Parkinson’s disease (PD) suggests that female sex steroids may promote dopaminergic neuron survival and protect them from degeneration. The glial cell line-derived neurotrophic factor (GDNF) is believed to be dopaminotrophic; thus it is considered as a potential therapeutic targ...

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Udgivet i:PLoS One
Main Authors: Enterría-Morales, Daniel, López-López, Ivette, López-Barneo, José, d’Anglemont de Tassigny, Xavier
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065215/
https://ncbi.nlm.nih.gov/pubmed/27741271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0164391
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