Corticosteroids Mediate Heart Failure-Induced Depression through Reduced σ1-Receptor Expression

Cardiovascular diseases are risk factors for depression in humans. We recently proposed that σ(1) receptor (σ(1)R) stimulation rescued cardiac hypertrophy and heart failure induced by transverse aortic constriction (TAC) in mice. Importantly, σ(1)R stimulation reportedly ameliorates depression-like...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Shinoda, Yasuharu, Tagashira, Hideaki, Bhuiyan, Md. Shenuarin, Hasegawa, Hideyuki, Kanai, Hiroshi, Zhang, Chen, Han, Feng, Fukunaga, Kohji
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065174/
https://ncbi.nlm.nih.gov/pubmed/27741227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163992
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